2022Year10moon13Harley-Davidson, Germany–University of Wittenberg (MLU) A group of researchers is working on a more practical way to repel mosquitoes, using3DPrinting technology to create mosquito repellent rings or any other wearable item. Researchers use a common repellent “IR3535» developed their product prototype.
△Scientists have developed a new3DPrinted wearable ring designed to repel mosquitoes and other insects long-term
In Africa, a child dies from malaria every two minutes. Mosquitoes and humans are at war. To help humans win, scientists are working on new strategies. Especially in Tanzania“The city of mosquitoes” Ifakala.IR3535Also called insect repellent (ethyl butylacetamidopropionate), this is a very effective broad-spectrum insect repellent. It has a good repellent effect on flies, lice, ants, mosquitoes, cockroaches, midges, horseflies, flat fleas, sand fleas, sand gnats, sandflies, cicadas, etc. , and can be used in different climatic conditions.
△Some mosquitoes can cause disease by transmitting the blood of malaria patients to normal people.
Traditionally, it is used in spray or lotion form and provides hours of protection. However,Androchand his team are looking for a more portable way to release the chemical slowly and continuously over a longer period of time, such as by encapsulating it in a wearable ring or bracelet.
△AdoptIR3535And3DPrinting polymers to create a convenient, fast and sustainable method to repel insects
to use3DPrinting technology is gaining innovation
IR3535The active ingredient, first “encapsulated” and shaped into the desired shape, such as a ring or other easily portable shape, can then be worn and release the repellent. In such a system, a solid polymer carries a liquid repellent that is slowly released into the environment. As a new approach, the team says:3DSolid insect repellent made of printing polymer, the insect repellent effect surpasses similar devices previously developed with different technologies.MLUofRené AndroschThe professor said: “ContainsIR3535The insect spray is very gentle on the skin and has been used worldwide for many years. This is why we use this chemical in our experiments. “The team used a3Dprinting technology capable of printing content containing up to25 million%repulsive3Dparts, and the repellent is lost minimally during the printing process, in a controlled manner, by inserting the repellent into the biodegradable polymer and shaping the material mixture in various ways.
△The team’s research results were published in the International Journal of Pharmacy, titled “Polymers/Anti-insect system (I-lactic acid)/Butylacetamidopropionic acid ethyl ester (PLLA/IR3535)of3DPrint” (portal)
3DThe main highlights of printing mosquito repellent rings or bracelets
*polymer/repulsivePLLA/IR3535can be transmitted3DPrint to obtain a drug delivery device;
*The maximum repellent load reached is25 million%；
*IR3535The evaporation rate at normal human body temperature is at least sustainable5-10sky.
Lead author of the studyMLUDoctoral student Du Fanfan said: “3DThe basic idea behind printing repellent rings is to slow the evaporation of the repellent and effectively create a repellent barrier. The rate at which the repellent evaporates depends on many different factors, including the temperature, concentration and structure of the polymer used. “After conducting various experiments and simulations, the team predicted that it would take more than a week for the repellent to work at body temperature.37 Celsius temperature evaporates completely. For samples containing small amounts of repellent, since the cooling step is quite rapid and the bed temperature is approx. 25 °C,PLLA Crystallization is inhibited below the glass transition temperature of the homogeneous polymer or repellent. At higher repellent concentrations, crystallinity slowly increases during storage after printing as the glass transition temperature decreases to near or even below room temperature. For all samples, regardless of the initial repellent concentration, the rate of repellent release increases with increasing temperature, and at room temperature the release time constant is approximately10sky. Although researchers have demonstrated that it is entirely possible to develop a wearable repellent, the rings and other shapes created for the study are currently prototypes.
Even though certain diseases caused by mosquito bites are now very rare in our country, for African countries, using3DPrinting technology, the introduction of this practical, fast and environmentally unaffected insect repellent technology still has great market prospects in the future. The researcher said additional studies are needed to determine how well the ring works in real-world conditions.
Source: Antarctic male
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